Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp51 | Adrenal medulla and NETs | ECE2018

Evolution of mesenteric metastasis in small intestinal neuroendocrine tumours (SI-NETs)

Blazevic Anela , Zandee Wouter T , Hofland Johannes , Franssen Gaston JH , van Velthuysen Marie-Louise F , Brabander Tessa , Feelders Richard A , de Herder Wouter W

Background: A metastatic mesenteric mass is a hallmark of small intestinal neuroendocrine tumours (SI-NETs). However, little is known about the evolution of a SI-NET-associated mesenteric mass over time.Methods: Retrospectively, 530 patients with proven SI-NET and ≥2 available CT-scans were assessed for clinical characteristics at diagnosis and the presence and growth of a mesenteric mass on every consecutive CT-scan until end of follow-up or resec...

ea0056gp230 | Thyroid Cancer - Diagnostics & Treatments | ECE2018

Peptide receptor radionuclide therapy in patients with medullary thyroid carcinoma: predictors and pitfalls

Beukhof Carolien , Brabander Tessa , van Nederveen Francien , van Velthuysen Loes , van Kemenade Folkert , de Rijke Yolanda , Froberg Lideke , Kam Boen , de Herder Wouter , Peeters Robin

Aim: To evaluate the effectiveness of Peptide Receptor Radionuclide Therapy with 177Lu-octreotate (PRRT) for medullary thyroid carcinoma (MTC).Background: There are few therapeutic options for progressive metastatic MTC. The Erasmus MC Center for Neuroendocrine Tumors has been at the forefront of developing PRRT for neuroendocrine tumors. PRRT has also been suggested to be a useful treatment for MTC, but evidence is very limited.<p class="...

ea0067o51 | Oral Presentations | EYES2019

The influence of sex on the evolution of mesenteric metastasis in small intestinal neuroendocrine tumours

Blažević Anela , Zandee Wouter , Hofland Johannes , Iyer Anand , Franssen Gaston JH , van Velthuysen Marie-Louise F , Brabander Tessa , Feelders Richard A , Hofland Leo J , de Herder Wouter W

Objective: A mesenteric mass with surrounding mesenteric fibrosis (MF) is a hallmark of small intestinal neuroendocrine tumours (SI-NETs) and known to induce abdominal complications. However, little is known on the evolution over time and the pathways involved in progression. Our aim was to assess the development of the metastatic mesenteric mass over time and find predictors for progression.Methods: Retrospectively, 530 patients with proven SI-NET and &...